Guide7.2
Sampling locations
Samples must represent the whole blend. For uniformity testing, take samples from at least 10 locations, covering top, middle and bottom layers, both legs and the apex of a V-blender, or the equivalent positions in other blenders and in drums.
| Practice | Requirement |
|---|---|
| Sample size | Typically 1–3 times the weight of one dosage unit for uniformity testing. |
| Sampling tool | A thief probe withdraws powder from a set depth without disturbing the rest of the blend. |
| Technique | Insert the probe smoothly; avoid dragging surface powder down the probe track. |
| Drum sampling | Sample from the start, middle and end of discharge to detect segregation. |
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